Viagra

Sildenafil is a selective PDE5 inhibitor developed in the 1990s to improve blood flow through vasodilation. It was initially researched for cardiovascular conditions but soon became widely used for treating erectile dysfunction (ED) due to its strong effect on penile circulation. By blocking the enzyme PDE5, sildenafil increases the level of cyclic guanosine monophosphate (cGMP) - a molecule responsible for relaxing smooth muscle cells in the vascular walls. This process allows for better blood flow to specific tissues, particularly in the corpus cavernosum of the penis, resulting in ... Show full